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KMID : 0882420160900010046
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Korean Journal of Medicine
2016 Volume.90 No. 1 p.46 ~ p.49
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Rapid Progression of Diabetic Glomerulosclerosis with Crescents to End-stage Renal Disease in Newly Diagnosed Type 2 Diabetes
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고영선:Ko Young-Sun
윤혜진:Yoon Hye-Jin/이은영:Lee Eun-Young/장기석:Jang Ki-Seok/이주학:Yi Joo-Hark/한상웅:Han Sang-Woong
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Abstract
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Diabetic nephropathy is a chronic microvascular complication of type 2 diabetes and the leading cause of end-stage renal disease. We report the case of a 34-year-old male, newly diagnosed with type 2 diabetes mellitus, who had advanced-stage nephropathy with glomerular crescents. A moderately-to-severely decreased glomerular filtration rate with nephrotic syndrome was seen at the time of diagnosis of diabetes. Proliferative diabetic retinopathy was detected, but there was no positive finding in serology tests for glomerulonephritis. Non-necrotizing cellular crescents and nodular glomerulosclerosis were observed in a kidney biopsy, and renal function declined rapidly to the end stage. We review data on diabetic glomerulosclerosis with cellular crescents and the rapid progression of nephropathy.
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KEYWORD
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Diabetic nephropathies, Disease progression, Pathology
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